How is a cerebrospinal fluid leak diagnosed?
Placement of tubes for epidural anesthesia or pain medications. People with connective tissue disorders like Ehlers-Danlos and Marfan syndromes. People between the ages of 30 and 40 years. With that being said, they are more common in certain groups of people, including: Who gets cerebrospinal fluid leaks?Īnyone can have a cerebrospinal fluid leak, and sometimes no cause can be found. They occur at a rate of approximately two to five cases for every 100,000 people, though this number is thought to be an underestimate. This can often be fixed by changing the setting of the shunt in the clinic.Īdditional Information How common is a cerebrospinal fluid leak?ĬSF leaks are rare. People with an intracranial or lumbar shunt device that is draining too much CSF also may experience intracranial hypotension. Evidence of CSF leakage on neuroimaging. A headache that has led to discovery the diagnosis of intracranial hypotension, along with the presence of low CSF pressure (<6cm H2O), or. A headache that has developed around the same time that low CSF pressure or a CSF leak occurred, or. This is diagnosed by meeting certain criteria, specifically: If spontaneous, it is referred to as spontaneous intracranial hypotension (SIH). CSF Leaks and Intracranial HypotensionĪ CSF leak can cause the pressure within the skull to drop to an abnormally low level, a condition called intracranial hypotension. The loss of CSF volume causes the normally buoyant brain to sag within the skull, often resulting in headaches and other neurological symptoms. 
A spontaneous CSF leak can be caused by a physical trauma or it can be idiopathic, which means that a clear cause is not identified. It cushions the brain, acting as a shock absorber, and serves as a vehicle for delivering nutrients to and removing waste from the brain.Ī CSF leak can occur spontaneously or after a lumbar puncture procedure. Cerebrospinal fluid is continuously produced in cavities in the brain called ventricles and absorbed into the bloodstream. Barrow-ASU Center for Preclinical ImagingĪ cerebrospinal fluid CSF leak, or CSF leak for short, is an escape of the colorless fluid that surrounds and protects the brain from the skull and spinal cord from the thecal sac (the tough covering surrounding the spinal cord) in the spine.Department of Translational Neuroscience.Department of ENT and Skull Base Surgery.Bioskills & Neurosurgery Research Laboratory.
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